2026 Week 4 Fantasy Football Matchup Preview: Friday–Monday Games

A massive 15-game Sunday slate headlined by a London opener, a pair of high-scoring showdowns, and a whole lot of injury news to sort through. The Week 4 slate runs Friday through Monday — here's what you need to know for every game.

Indianapolis Colts at Washington Commanders

Jayden Daniels (Questionable) is OUT. Head coach Dan Quinn ruled Daniels out Friday with his dislocated elbow, meaning Marcus Mariota starts again. That's a meaningful downgrade for everyone in the Washington passing game. Terry McLaurin (Questionable - turned up on the injury list today) and Stefon Diggs are playable in PPR given 7+ targets each, but Mariota's ceiling is limited. Rachaad White is OUT. Fire up Bill (Jacory Crosley-Merritt) this week.

On the Indianapolis side, The Commanders' defense allows just 9.75 PPR points per game to RBs (28th-most in the league — that means RBs have it tough), so Jonathan Taylor faces a stiff test on the ground. Taylor is averaging 25 touches per game with solid production (63.5 PPR points through 3 games), so the role is locked in — but the matchup should suppress his ceiling. Tyler Warren is the real weapon: 7.3 targets per game, 6 receptions per game, and 39.4 PPR points through 3 games. Washington is the single worst defense against TEs in the league, allowing 22 PPR points per game (rank 1 of 32 — meaning most allowed). Lock him in. Josh Downs draws a tough CB matchup per reports, but his 8 targets per game make him worth starting in PPR formats regardless.

Tennessee Titans at Baltimore Ravens

Tennessee is 0-3 and the Ravens are favored at home coming off a last-second road win. Baltimore's defense isn't a problem for Lamar Jackson's offense — the Titans allow 28.75 PPR points per game to WRs (10th-most), and Zay Flowers is fully healthy after practicing fully Thursday following a hamstring injury. Flowers' snap share has been modest (31.1% this season) but he's averaged 6 targets and 5 catches per game in 2 appearances — the role is real when healthy and this matchup is good. Start him in PPR.

Derrick Henry is a must-start everywhere: 23.7 touches per game, 74.9 PPR points through 3 weeks, and leading the NFL with 6 rushing TDs per reports. The Titans' D allows 13.4 PPR points per game to RBs (20th) — nothing scary there. On the Tennessee side, Cam Ward faces a defense that has been stingy against QBs (rank 19). Carnell Tate has a reported tough CB matchup against Nate Wiggins. Wan'Dale Robinson (6 targets/game) is the more reliable volume play in PPR.

New England Patriots at Buffalo Bills

Buffalo's defense is a smash spot for skill positions: it allows 40.25 PPR points per game to WRs (rank 2 of 32 — second-most in the league) and 33.9 points per game to RBs (rank 1 — the absolute most). DJ Moore is questionable (injury status flagged), which matters — he's averaging 9 targets per game but converting at a low rate (5.5 catches per game), so his production hasn't matched the volume. If he plays, that target share is real and the matchup is elite. James Cook is a confident start on role alone: 20.7 touches per game, 50.2 PPR points through 3 games. Josh Allen is an every-format lock.

New England's offense is in chaos. Drake Maye has struggled badly enough that reports surfaced of tension with the coaching staff. The Patriots' D allows just 20.5 PPR points per game to WRs (rank 22 — below average allowed) and 11.5 to RBs (rank 24). Rhamondre Stevenson and TreVeyon Henderson split the backfield (13.3 and 12.5 avg touches, respectively) — neither has a defined lead role, and the matchup doesn't bail either out. Dalton Kincaid is the sneaky value play on the Bills: 5.7 targets and 4.7 catches per game with 44.3 PPR points through 3 weeks.

New York Jets at Chicago Bears

Breece Hall is Out. That pushes Braelon Allen into a bigger role, but his volume (7.7 touches/game) has been genuinely thin. The Jets' defense allows just 4.4 PPR points per game to RBs (rank 32 — fewest in the league), so even if Allen gets more work, don't expect big RB numbers on the Chicago side either. Kenyon Sadiq is Questionable — the rookie TE broke out in Week 3 with 7 catches, 105 yards, and a TD; he's worth monitoring closely before lock.

Garrett Wilson is the only Jets player worth trusting: 9 targets and 7 catches per game, 57.3 PPR points in 3 games, and a great volume-to-production relationship. Start him with confidence in PPR. The Bears' QB situation is murky — signs point to Tyson Bagent starting with coach Ben Johnson trying to obscure the decision. D'Andre Swift is Questionable with solid volume (20.7 touches/game) and production (56.1 PPR points through 3 games) when healthy — he's worth starting if active, but have a backup ready. Luther Burden has earned his target share (7.7/game) and is fine as a flex in PPR.

Jacksonville Jaguars at Cincinnati Bengals

This game has a high over/under per analyst reports, and both offenses have real fantasy value. Trevor Lawrence is playing well and is a must start against a defense that has regressed a bit after starting out strong in weeks 1 and 2. Ja'Marr Chase is the centerpiece: 8.3 targets and 6 catches per game, 54.5 PPR points through 3 games, and a clean start in every format. Chase Brown is also a comfortable start — 19.7 touches, 4.3 targets, and 3.3 catches per game (38.9 PPR points). The passing-plus-rushing volume makes him PPR-relevant in particular.

Jacksonville's defense allows just 8.1 PPR points per game to RBs (rank 30 — near-fewest), so Bengals RBs face a tough matchup in standard scoring. On the Jaguars' side, Parker Washington (7.7 targets/game, 49.1 PPR points through 3 games) is the reliable volume play. Bhayshul Tuten has 16 touches per game and 41 PPR points — fine as a flex, though the D limits upside. Jakobi Meyers is Questionable — if he misses it, Washington's PPR value climbs further.

Dallas Cowboys at Houston Texans

This game is played indoors, so weather is not a factor. Houston's defense allows 41.25 PPR points per game to WRs (rank 1 — the most in the league). CeeDee Lamb is a must-start in every format: 8.3 targets and 6.7 catches per game, 70.9 PPR points this season. George Pickens is also live — same 8.3 targets per game and this matchup is elite for WRs. Dak Prescott (64.1 PPR points through 3 games) has WR2 appeal in two-QB leagues here. Javonte Williams averages 17.7 touches and 3.3 catches per game (50.5 PPR points) — solid flex.

Nico Collins is Questionable and has played just one game this season. When healthy he saw 10 targets, 7 catches, and 72.2% snap share in that game. Monitor his status, but don't start him blind given just one game of data. David Montgomery owns the Texans' goal-line role — he's taken 3 of 4 carries inside the 5 and scored twice, with 14.7 touches per game and 40.1 PPR points. The Cowboys' D allows 20.8 PPR points per game to RBs (rank 12), so Montgomery is a confident start.

Arizona Cardinals at New York Giants

Trey McBride is the story of this game. He's averaging 11.3 targets and 8.7 catches per game — elite usage — with 59.1 PPR points through 3 games. New York allows 14.55 PPR points per game to TEs (rank 8 — above-average allowed), a good-not-great matchup, but McBride's volume alone makes him a top-5 TE start. Jeremiyah Love has 17 touches per game and 42.4 PPR points — solid start given the Giants allow 20.3 PPR points per game to RBs (rank 14).

On New York's side, Jameis Winston starts with J.J. McCarthy newly acquired but not yet playing. Cam Skattebo has grown into a feature-back role (19 touches/game, 36.6 PPR points) against a Cardinals defense allowing just 9.2 PPR points per game to RBs (rank 29 — near-fewest). That's a tough matchup — temper expectations in standard, though his pass-catching (3.5 catches/game) keeps him relevant in PPR. Isaiah Likely has 7.7 targets per game and 39.4 PPR points — solid TE2 with the Giants allowing 35.8 PPR points per game to WRs (rank 5 — a lot), Malik Nabers is worth starting despite the modest production-to-date (21.6 PPR points through 3 games) since his 6.3 targets/game indicate the volume is there and hasn't fully converted yet.

Los Angeles Rams at Philadelphia Eagles

Puka Nacua is Questionable and has played just one game this season. DeVonta Smith is Questionable with a hamstring injury after missing back-to-back practices — treat her as a genuine game-time decision. If Smith misses it, Jalen Hurts loses his highest-volume target (9 targets/game, 48.5 PPR points) and fantasy value shifts around. Saquon Barkley is a concern regardless: just 12.3 touches per game and 21 PPR points through 3 games — that's low usage for a player of his profile, and the production hasn't been there. The Rams allow 11.65 PPR points per game to RBs (rank 23), so the matchup doesn't help. Fade Barkley until the role clarifies.

Kyren Williams has real usage (16.3 touches, 3.7 catches/game) and 53 PPR points through 3 games — comfortable start. Davante Adams averages 9.7 targets and 6 catches per game (65.8 PPR points) — the volume is elite and production reflects it. Start him in all formats. If Nacua plays, he saw 9 targets in his one game; if he sits, Adams and the Rams' secondary options absorb more of the target share.

Green Bay Packers at Tampa Bay Buccaneers

Tampa Bay's defense is a nightmare for WRs — it allows just 9.55 PPR points per game to that position (rank 31 — second-fewest in the league). Christian Watson leads Green Bay's WRs with 9.7 targets per game and 69.4 PPR points, but this matchup is legitimately bad. Matthew Golden (10 targets/game, 46.3 PPR points) faces the same wall. Downgrade both in single-game DFS; they're startable given the volume and with Jayden Reed out for the season, but don't expect ceilings. Tucker Kraft has 5.7 targets per game but only 19.6 PPR points through 3 games — the volume hasn't converted, which is the "trust the role" scenario. He's a TE2 in PPR

Bucky Irving is Questionable — he's been Tampa Bay's best RB value with 17.7 touches and 4.3 catches per game (41.1 PPR points). If he plays, the Packers allow 26.8 PPR points per game to RBs (rank 6 — a lot of points allowed), so he's a great matchup play when healthy. Start Kenny Gainwell if Irving is ruled out. Stay away from Tampa Bay WRs and TEs this week with UDFA Jalon Daniels filling in as QB.

Miami Dolphins at Minnesota Vikings

This game is played indoors, so weather is not a factor. The Vikings' defense has allowed 29.75 PPR points per game to RBs (rank 4 — fourth-most in the league), and the Dolphins' backfield situation is murky without De'Von Achane (season-ending ACL). Ollie Gordon and Jaylen Wright (Questionable) may split snaps — proceed with caution on both. Malik Washington is the most reliable Dolphins fantasy asset: 7.7 targets, 4 catches/game, 26.1 PPR points in good volume but limited conversion — a PPR-only flex in a good matchup. Caleb Douglas is Questionable.

On Minnesota's side, Justin Jefferson is Questionable with an ankle injury he suffered in Week 3. His snap share (68.1%) and targets (5.7/game) have already been modest for a player of his caliber — if he's less than 100%, fade him. Aaron Jones is a quiet-but-real PPR asset: 19 touches and 5 catches per game, 34.7 PPR points — Miami allows 29.75 per game to RBs, so he's a start. Kyler Murray has played only 2 games (12 PPR points total) — limited data, limited trust.

Kansas City Chiefs at Las Vegas Raiders

This game is played indoors, so weather is not a factor. The Raiders are 3-0 and playing at home in a game with genuine buzz. Kenneth Walker is the Chiefs' top RB value: 25.3 touches and 6 targets per game, 79.2 PPR points through 3 games — the usage and production are both locked in. Las Vegas allows just 12.1 PPR points per game to WRs (rank 28 — near-fewest), which is a concern for Rashee Rice and Xavier Worthy. Both have the target volume (5.7 and 5/game respectively), but this matchup suppresses WR ceilings.

Travis Kelce has 6 targets and 4.7 catches per game with 49.1 PPR points — the Raiders allow 5.4 PPR points per game to TEs (rank 27 — third-fewest). Even Kelce has a tough matchup here. On the Raiders' side, Brock Bowers is the smash play: 13 targets and 10 catches in his one game this season — the Chiefs allow 8.65 PPR points per game to TEs (rank 20), which is just average, but Bowers' usage is so dominant that he starts in every format. Ashton Jeanty has 25.3 touches per game and 55.3 PPR points — the Kansas City defense allows 20.45 PPR points per game to RBs (rank 13), a neutral matchup. Start him confidently.

Los Angeles Chargers at Seattle Seahawks

Jaxson Smith-Njigba is on a heater: 12 targets and 9 catches per game, 104.1 PPR points through 3 games — the highest production total of any player on this slate. The Chargers allow 23.4 PPR points per game to WRs (rank 19 — slightly above average), which is not special, but JSN's usage is so extreme that matchup barely matters. Lock him in every format.

Jadarian Price is Questionable after missing Thursday's practice with a chest injury. He's averaged 10.7 touches per game with two fumbles noted in the injury news — a precarious situation. Zach Charbonnet has been designated to return from PUP but is not eligible to play until Week 5. If Price is out, Emanuel Wilson will be the next man up and worth rostering. On the Chargers' side, Ladd McConkey is Questionable — he has 5 targets and 4 catches per game (36.3 PPR points), genuine volume that's converting well. If he plays, he's a PPR start. Omarion Hampton has 17.3 touches per game (31.4 PPR points) — the Seahawks allow 12.4 PPR points per game to RBs (rank 22), a neutral matchup. He's a flex play.

Denver Broncos at San Francisco 49ers

San Francisco's defense is tough on WRs — it allows just 9.9 PPR points per game to that position (rank 30 — near-fewest) and only 9.5 to QBs (rank 24). The Broncos' passing game is already underwhelming (Jaylen Waddle: 6.7 targets but just 3.7 catches/game, 29.4 PPR points; Courtland Sutton: 5.3 targets but only 2.7 catches/game, 16.2 PPR points). The volume is there but the conversion is poor for both — the "trust the role" case barely applies when the matchup is this punishing. Fade both.

RJ Harvey averages 5.5 targets and 5 receptions per game in 2 games played — elite pass-catching volume for a back — but the 49ers allow 22.6 PPR points per game to RBs (rank 10), a real matchup to attack in PPR. J.K. Dobbins splits time (12 touches/game, 42.1% snap share) and is a lesser option. On the 49ers' side, Christian McCaffrey's role is locked in (16 touches and 4.3 catches/game, 58 PPR points). Mike Evans is Questionable with ribs; he's been averaging 5.3 targets and 4 catches per game (37.7 PPR points). Isaac Guerendo is on PUP and not playing. George Kittle has 5.3 targets and 4 catches per game (47.4 PPR points) — Denver allows 22.6 PPR points per game to TEs (rank 10), a decent matchup. Start him. Brock Purdy (81.9 PPR points through 3 games) remains a fantasy QB1 even with a tough WR matchup, given his rushing floor.

Detroit Lions at Carolina Panthers

This is the other high-ceiling game on the slate. Carolina's defense allows 36.8 PPR points per game to WRs (rank 4 — fourth-most), 30.75 PPR points per game to RBs (rank 3 — third-most), and 33.01 to QBs (rank 1 — the most in the league). Basically the entire Detroit offense is in a smash spot.

Jahmyr Gibbs is the top play on the board: 27.7 touches and 6 catches per game, 98.3 PPR points through 3 games, and per reports he handles all seven of Detroit's RB carries inside the 5 — the goal-line role is his. Amon-Ra St. Brown averages 11.7 targets and 7.7 catches per game (75.8 PPR points) — elite usage, elite production, elite matchup. Jared Goff has 65.6 PPR points through 3 games and gets the best possible QB matchup this week. Sam LaPorta (6.3 targets/game, 34.4 PPR points) is also a TE1 here.

On Carolina's side, Chuba Hubbard has carved out genuine volume (16.7 touches and 3 catches/game, 53.1 PPR points) and Detroit allows 22.95 PPR points per game to RBs (rank 9) — a playable matchup. Tetairoa McMillan has 7.7 targets/game but only 4 catches/game and 29.3 PPR points — the volume hasn't converted, which in PPR is the buy-low case. Jalen Coker is Questionable — he's been the volume leader in the Carolina WR room (7.3 targets, 6 catches/game, 52.2 PPR points). If he plays, he's a start. If he misses, McMillan's value rises.

Atlanta Falcons at New Orleans Saints

This game is played indoors, so weather is not a factor. Bijan Robinson is the headliner: 26.3 touches and 4.3 catches per game (77.7 PPR points through 3 games), with the Saints allowing 28.95 PPR points per game to RBs (rank 5 — fifth-most). He's a top-3 RB this week in all formats. The Saints' defense allows 11.2 PPR points per game to WRs (rank 29 — near-fewest), which is a real concern for Drake London, who averages 5 catches per game (42.8 PPR points) with solid usage. The volume is real, but this matchup will suppress London's ceiling — he's a hold in PPR, borderline sit in standard.

Atlanta's D allows just 6.07 PPR points per game to QBs (rank 31 — second-fewest) but Tyler Shough has been outstanding (72.4 PPR points through 3 games, 4.7 rush attempts/game adding a floor). He's a fantasy QB2 with upside. Chris Olave is the standout start on the Saints: 12 targets and 9 catches per game, 70.5 PPR points — the Atlanta D allows 11.2 PPR points per game to WRs (rank 29), but Olave's target volume is so extreme (top-3 on the slate) that he starts in PPR regardless. Devaughn Vele (7.3 targets, 5 catches/game, 38.2 PPR points) is a PPR flex with volume that's produced. Juwan Johnson (6.3 targets, 5 catches/game, 48.3 PPR points) is a TE1 with the Atlanta defense allowing 19.55 PPR points per game to TEs (rank 2 — second-most). Start him.