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2026 Week 5 Fantasy Football: DJ Moore Questionable, Joshua Palmer Out for Bills vs. Rams

A shoulder injury has DJ Moore's status up in the air for Monday night, while Joshua Palmer is already ruled out — here's what it means for your lineup.

According to ProFootballTalk (NBC Sports), Bills wide receiver DJ Moore is listed as questionable for Monday night's game against the Rams due to a shoulder injury that kept him off the practice field Thursday and Friday. Moore did make it to Saturday's practice, though he wore a red non-contact jersey. Head coach Joe Brady confirmed Moore will travel to Los Angeles, meaning a final call on his status could come closer to kickoff. Fellow Bills wideout Joshua Palmer (shoulder) has been ruled out entirely — the first game he'll miss this season.

DJ Moore

The "questionable" tag after two missed practice days and a limited Saturday is a real concern — don't treat this as a standard DNP-Wednesday situation. If Moore is a must-start on your roster, have a backup plan ready before Monday night's kickoff. If you have a viable alternative, this is a week to use them. Moore traveling to LA keeps the door open, but a red jersey on Saturday is not the green light you want heading into a big primetime spot.

Joshua Palmer

Palmer is ruled out, which makes Moore's status even more consequential for the Bills' passing game — the two injuries are directly connected. If Moore plays, he absorbs targets that might otherwise have gone to Palmer, which is a modest boost. If Moore is also out, the Bills' receiving corps takes a significant hit and targets will need to be redistributed to players further down the depth chart. The source story does not specify who those players are, so monitor the Bills' active roster once it's announced. Dynasty managers can largely set aside Palmer's single absence, but redraft owners should not count on him this week.

Data: real stats via Sleeper, projections via FantasyPros.